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Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune‐Oncology Therapies: A Tutorial for Clinical Pharmacologists

Application of contemporary molecular biology techniques to clinical samples in oncology resulted in the accumulation of unprecedented experimental data. These “omics” data are mined for discovery of therapeutic target combinations and diagnostic biomarkers. It is less appreciated that omics resourc...

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Detalles Bibliográficos
Autores principales: Lazarou, Georgia, Chelliah, Vijayalakshmi, Small, Ben G., Walker, Michael, van der Graaf, Piet H., Kierzek, Andrzej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158209/
https://www.ncbi.nlm.nih.gov/pubmed/31955413
http://dx.doi.org/10.1002/cpt.1786