Lupeol alleviates coxsackievirus B3-induced viral myocarditis in mice via downregulating toll-like receptor 4

OBJECTIVES: To investigate the effect of lupeol in a mouse model of viral myocarditis induced by coxsackie virus B3 (CVB3). METHODS: Mice were separated into controls (DMEM, n = 20) and CVB3 infected groups (i.e., untreated CVB3 [n = 40]; CVB3 + lupeol 50 mg/kg [n = 40]; CVB3 + lupeol 100 mg/kg [n =...

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Detalles Bibliográficos
Autores principales: Xu, Ming, Li, Xiaoyong, Song, Laichun, Tao, Chao, Fang, Jihui, Tao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158257/
https://www.ncbi.nlm.nih.gov/pubmed/32290748
http://dx.doi.org/10.1177/0300060520910908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158257/
https://www.ncbi.nlm.nih.gov/pubmed/32290748
http://dx.doi.org/10.1177/0300060520910908

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