Genetic Adjuvants in Replicating Single-Cycle Adenovirus Vectors Amplify Systemic and Mucosal Immune Responses against HIV-1 Envelope

Most infections occur at mucosal surfaces. Providing a barrier of protection at these surfaces may be a useful strategy to combat the earliest events in infection when there are relatively few pathogens to address. The majority of vaccines are delivered systemically by the intramuscular (IM) route....

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Detalles Bibliográficos
Autores principales: Matchett, William E., Malewana, Goda Baddage Rakitha, Mudrick, Haley, Medlyn, Michael J., Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158672/
https://www.ncbi.nlm.nih.gov/pubmed/32024265
http://dx.doi.org/10.3390/vaccines8010064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158672/
https://www.ncbi.nlm.nih.gov/pubmed/32024265
http://dx.doi.org/10.3390/vaccines8010064

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