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The Dual-Specificity Kinase DYRK1A Modulates the Levels of Cyclin L2 To Control HIV Replication in Macrophages

HIV replication in macrophages contributes to the latent viral reservoirs, which are considered the main barrier to HIV eradication. Few cellular factors that facilitate HIV replication in latently infected cells are known. We previously identified cyclin L2 as a critical factor required by HIV-1 an...

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Detalles Bibliográficos
Autores principales: Kisaka, Javan K., Ratner, Lee, Kyei, George B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158737/
https://www.ncbi.nlm.nih.gov/pubmed/31852782
http://dx.doi.org/10.1128/JVI.01583-19