Conserved strategies for pathogen evasion of cGAS–STING immunity

The cyclic GMP–AMP synthase (cGAS)– Stimulator of Interferon Genes (STING) pathway of cytosolic DNA sensing allows mammalian cells to detect and respond to infection with diverse pathogens. Pathogens in turn encode numerous factors that inhibit nearly all steps of cGAS–STING signal transduction. Fro...

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Detalles Bibliográficos
Autores principales: Eaglesham, James B, Kranzusch, Philip J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158794/
https://www.ncbi.nlm.nih.gov/pubmed/32339908
http://dx.doi.org/10.1016/j.coi.2020.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158794/
https://www.ncbi.nlm.nih.gov/pubmed/32339908
http://dx.doi.org/10.1016/j.coi.2020.04.002

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