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YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response

YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently in the T regulatory (Treg) subset of CD4+ cells. Th...

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Detalles Bibliográficos
Autores principales: Lebid, Andriana, Chung, Liam, Pardoll, Drew M., Pan, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158852/
https://www.ncbi.nlm.nih.gov/pubmed/32322254
http://dx.doi.org/10.3389/fimmu.2020.00580