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YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response
YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently in the T regulatory (Treg) subset of CD4+ cells. Th...
Autores principales: | Lebid, Andriana, Chung, Liam, Pardoll, Drew M., Pan, Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158852/ https://www.ncbi.nlm.nih.gov/pubmed/32322254 http://dx.doi.org/10.3389/fimmu.2020.00580 |
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