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[(18)F]Atorvastatin: synthesis of a potential molecular imaging tool for the assessment of statin-related mechanisms of action

BACKGROUND: Statins are lipid-lowering agents that inhibit cholesterol synthesis and are clinically used in the primary and secondary prevention of cardiovascular diseases. However, a considerable group of patients does not respond to statin treatment, and the reason for this is still not completely...

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Detalles Bibliográficos
Autores principales: Clemente, Gonçalo S., Rickmeier, Jens, Antunes, Inês F., Zarganes-Tzitzikas, Tryfon, Dömling, Alexander, Ritter, Tobias, Elsinga, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158976/
https://www.ncbi.nlm.nih.gov/pubmed/32296962
http://dx.doi.org/10.1186/s13550-020-00622-4