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[(18)F]Atorvastatin: synthesis of a potential molecular imaging tool for the assessment of statin-related mechanisms of action
BACKGROUND: Statins are lipid-lowering agents that inhibit cholesterol synthesis and are clinically used in the primary and secondary prevention of cardiovascular diseases. However, a considerable group of patients does not respond to statin treatment, and the reason for this is still not completely...
Autores principales: | Clemente, Gonçalo S., Rickmeier, Jens, Antunes, Inês F., Zarganes-Tzitzikas, Tryfon, Dömling, Alexander, Ritter, Tobias, Elsinga, Philip H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158976/ https://www.ncbi.nlm.nih.gov/pubmed/32296962 http://dx.doi.org/10.1186/s13550-020-00622-4 |
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