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Neurokinin 3 Receptor Antagonists Do Not Increase FSH or Estradiol Secretion in Menopausal Women

BACKGROUND: Neurokinin 3 receptor (NK3R) antagonism is a promising novel treatment for menopausal flashes. However, to avoid adverse hormonal effects it is clinically important to first confirm whether gonadotropin and estradiol concentrations change as a result of their administration. METHODS: Sin...

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Detalles Bibliográficos
Autores principales: Prague, Julia K, Abbara, Ali, Comninos, Alexander N, Jayasena, Channa N, Higham, Claire E, Adaway, Jo, Keevil, Brian G, Veldhuis, Johannes D, Dhillo, Waljit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159071/
https://www.ncbi.nlm.nih.gov/pubmed/32318647
http://dx.doi.org/10.1210/jendso/bvz009