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Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis

Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are believed to be highly time-variant. However, current approaches measure elemental biomarkers at a few discrete time-points, ignoring complex higher-order dynamical features. To study dynamical properties of eleme...

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Detalles Bibliográficos
Autores principales: Curtin, Paul, Austin, Christine, Curtin, Austen, Gennings, Chris, Figueroa-Romero, Claudia, Mikhail, Kristen A., Botero, Tatiana M., Goutman, Stephen A., Feldman, Eva L., Arora, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159190/
https://www.ncbi.nlm.nih.gov/pubmed/32294079
http://dx.doi.org/10.1371/journal.pcbi.1007773