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Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis
Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are believed to be highly time-variant. However, current approaches measure elemental biomarkers at a few discrete time-points, ignoring complex higher-order dynamical features. To study dynamical properties of eleme...
Autores principales: | Curtin, Paul, Austin, Christine, Curtin, Austen, Gennings, Chris, Figueroa-Romero, Claudia, Mikhail, Kristen A., Botero, Tatiana M., Goutman, Stephen A., Feldman, Eva L., Arora, Manish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159190/ https://www.ncbi.nlm.nih.gov/pubmed/32294079 http://dx.doi.org/10.1371/journal.pcbi.1007773 |
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