Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans

Charcot-Marie-Tooth (CMT) disease is an inherited peripheral motor and sensory neuropathy. The disease is divided into demyelinating (CMT1) and axonal (CMT2) neuropathies, and although we have gained molecular information into the details of CMT1 pathology, much less is known about CMT2. Due to its...

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Detalles Bibliográficos
Autores principales: Soh, Ming S., Cheng, Xinran, Vijayaraghavan, Tarika, Vernon, Arwen, Liu, Jie, Neumann, Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159224/
https://www.ncbi.nlm.nih.gov/pubmed/32294113
http://dx.doi.org/10.1371/journal.pone.0231600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159224/
https://www.ncbi.nlm.nih.gov/pubmed/32294113
http://dx.doi.org/10.1371/journal.pone.0231600

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