A compound attributes-based predictive model for drug induced liver injury in humans

Drug induced liver injury (DILI) is one of the key safety concerns in drug development. To assess the likelihood of drug candidates with potential adverse reactions of liver, we propose a compound attributes-based approach to predicting hepatobiliary disorders that are routinely reported to US Food...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Gao, Hua, He, Yudong D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159228/
https://www.ncbi.nlm.nih.gov/pubmed/32294131
http://dx.doi.org/10.1371/journal.pone.0231252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159228/
https://www.ncbi.nlm.nih.gov/pubmed/32294131
http://dx.doi.org/10.1371/journal.pone.0231252

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