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Prenatal androgen induced lean PCOS impairs mitochondria and mRNA profiles in oocytes

Polycystic ovary syndrome (PCOS) is the most common ovulatory defect in women. Although most PCOS patients are obese, a subset of PCOS women are lean but show similar risks for adverse fertility outcomes. A lean PCOS mouse model was created using prenatal androgen administration. This developmentall...

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Detalles Bibliográficos
Autores principales: Chappell, Neil R, Zhou, Beth, Schutt, Amy K, Gibbons, William E, Blesson, Chellakkan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159265/
https://www.ncbi.nlm.nih.gov/pubmed/32101528
http://dx.doi.org/10.1530/EC-19-0553