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Autonomous synthesis and assembly of a ribosomal subunit on a chip

Ribosome biogenesis is an efficient and complex assembly process that has not been reconstructed outside a living cell so far, yet is the most critical step for establishing a self-replicating artificial cell. We recreated the biogenesis of Escherichia coli’s small ribosomal subunit by synthesizing...

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Detalles Bibliográficos
Autores principales: Levy, Michael, Falkovich, Reuven, Daube, Shirley S., Bar-Ziv, Roy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159907/
https://www.ncbi.nlm.nih.gov/pubmed/32494616
http://dx.doi.org/10.1126/sciadv.aaz6020