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Cryo-EM structure of the human heteromeric amino acid transporter b(0,+)AT-rBAT

Heteromeric amino acid transporters (HATs) catalyze the transmembrane movement of amino acids, comprising two subunits, a heavy chain and a light chain, linked by a disulfide bridge. The b(0,+)AT (SLC7A9) is a representative light chain of HATs, forming heterodimer with rBAT, a heavy chain which med...

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Detalles Bibliográficos
Autores principales: Yan, Renhong, Li, Yaning, Shi, Yi, Zhou, Jiayao, Lei, Jianlin, Huang, Jing, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159911/
https://www.ncbi.nlm.nih.gov/pubmed/32494597
http://dx.doi.org/10.1126/sciadv.aay6379