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2.7 Å cryo-EM structure of rotavirus core protein VP3, a unique capping machine with a helicase activity

In many viruses, including rotavirus (RV), the major pathogen of infantile gastroenteritis, capping of viral messenger RNAs is a pivotal step for efficient translation of the viral genome. In RV, VP3 caps the nascent transcripts synthesized from the genomic dsRNA segments by the RV polymerase VP1 wi...

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Detalles Bibliográficos
Autores principales: Kumar, Dilip, Yu, Xinzhe, Crawford, Sue E., Moreno, Rodolfo, Jakana, Joanita, Sankaran, Banumathi, Anish, Ramakrishnan, Kaundal, Soni, Hu, Liya, Estes, Mary K, Wang, Zhao, Prasad, B. V. Venkataram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159914/
https://www.ncbi.nlm.nih.gov/pubmed/32494598
http://dx.doi.org/10.1126/sciadv.aay6410