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Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering

Gene expression in response to stimuli underlies many fundamental processes. However, how transcription is regulated under these scenarios is largely unknown. Here, we find a previously unknown role of nuclear actin in transcriptional regulation. The RNA-seq data reveal that nuclear actin is require...

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Detalles Bibliográficos
Autores principales: Wei, Mian, Fan, Xiaoying, Ding, Miao, Li, Ruifeng, Shao, Shipeng, Hou, Yingping, Meng, Shaoshuai, Tang, Fuchou, Li, Cheng, Sun, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159918/
https://www.ncbi.nlm.nih.gov/pubmed/32494599
http://dx.doi.org/10.1126/sciadv.aay6515