Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

Coordinated assembly and disassembly of integrin-mediated focal adhesions (FAs) is essential for cell migration. Many studies have shown that FA disassembly requires Ca(2+) influx, however our understanding of this process remains incomplete. Here, we show that Ca(2+) influx via STIM1/Orai1 calcium...

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Detalles Bibliográficos
Autores principales: D'Souza, Ryan S, Lim, Jun Y, Turgut, Alper, Servage, Kelly, Zhang, Junmei, Orth, Kim, Sosale, Nisha G, Lazzara, Matthew J, Allegood, Jeremy, Casanova, James E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159923/
https://www.ncbi.nlm.nih.gov/pubmed/32234213
http://dx.doi.org/10.7554/eLife.54113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159923/
https://www.ncbi.nlm.nih.gov/pubmed/32234213
http://dx.doi.org/10.7554/eLife.54113

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