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Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer

WNT2 acts as a pro-angiogenic factor in placental vascularization and increases angiogenesis in liver sinusoidal endothelial cells (ECs) and other ECs. Increased WNT2 expression is detectable in many carcinomas and participates in tumor progression. In human colorectal cancer (CRC), WNT2 is selectiv...

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Detalles Bibliográficos
Autores principales: Unterleuthner, Daniela, Neuhold, Patrick, Schwarz, Katharina, Janker, Lukas, Neuditschko, Benjamin, Nivarthi, Harini, Crncec, Ilija, Kramer, Nina, Unger, Christine, Hengstschläger, Markus, Eferl, Robert, Moriggl, Richard, Sommergruber, Wolfgang, Gerner, Christopher, Dolznig, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160098/
https://www.ncbi.nlm.nih.gov/pubmed/31667643
http://dx.doi.org/10.1007/s10456-019-09688-8