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Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma

Asthma is a chronic and genetically complex respiratory disease that affects over 300 million people worldwide. Here, we report a genome-wide analysis for asthma using data from the UK Biobank and the Trans-National Asthma Genetic Consortium. We identify 66 previously unknown asthma loci and demonst...

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Detalles Bibliográficos
Autores principales: Han, Yi, Jia, Qiong, Jahani, Pedram Shafiei, Hurrell, Benjamin P., Pan, Calvin, Huang, Pin, Gukasyan, Janet, Woodward, Nicholas C., Eskin, Eleazar, Gilliland, Frank D., Akbari, Omid, Hartiala, Jaana A., Allayee, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160128/
https://www.ncbi.nlm.nih.gov/pubmed/32296059
http://dx.doi.org/10.1038/s41467-020-15649-3