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XPO5 promotes primary miRNA processing independently of RanGTP

XPO5 mediates nuclear export of miRNA precursors in a RanGTP-dependent manner. However, XPO5-associated RNA species have not been determined globally and it is unclear whether XPO5 has any additional functions other than nuclear export. Here we show XPO5 pervasively binds to double-stranded RNA regi...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Lee, Jerome E., Riemondy, Kent, Yu, Yang, Marquez, Steven M., Lai, Eric C., Yi, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160132/
https://www.ncbi.nlm.nih.gov/pubmed/32296071
http://dx.doi.org/10.1038/s41467-020-15598-x