Cargando…
Resveratrol attenuates hypoxia-induced neuronal cell death, inflammation and mitochondrial oxidative stress by modulation of TRPM2 channel
Hypoxia (HYPX) induced-overload Ca(2+) entry results in increase of mitochondrial oxidative stress, inflammation and apoptosis in several neurons. Ca(2+) permeable TRPM2 channel was gated by ADP-ribose (ADPR) and reactive oxygen species (ROS), although its activity was modulated in HYPX-exposed neur...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160154/ https://www.ncbi.nlm.nih.gov/pubmed/32296107 http://dx.doi.org/10.1038/s41598-020-63577-5 |