Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes

Sublytic levels of C5b-9 increase the survival of oligodendrocytes (OLGs) and induce the cell cycle. We have previously observed that SIRT1 co-localizes with surviving OLGs in multiple sclerosis (MS) plaques, but it is not yet known whether SIRT1 is involved in OLGs survival after exposure to sublyt...

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Detalles Bibliográficos
Autores principales: Tatomir, Alexandru, Rao, Gautam, Boodhoo, Dallas, Vlaicu, Sonia I., Beltrand, Austin, Anselmo, Freidrich, Rus, Violeta, Rus, Horea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160252/
https://www.ncbi.nlm.nih.gov/pubmed/32328069
http://dx.doi.org/10.3389/fimmu.2020.00619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160252/
https://www.ncbi.nlm.nih.gov/pubmed/32328069
http://dx.doi.org/10.3389/fimmu.2020.00619

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