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Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle

With the ability to switch between proliferative and contractile phenotype, airway smooth muscle (ASM) cells can contribute to the progression of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), in which airway obstruction is associated with ASM hypertrophy and hyperc...

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Detalles Bibliográficos
Autores principales: Baarsma, Hoeke A., Han, Bing, Poppinga, Wilfred J., Driessen, Saskia, Elzinga, Carolina R. S., Halayko, Andrew J., Meurs, Herman, Maarsingh, Harm, Schmidt, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160303/
https://www.ncbi.nlm.nih.gov/pubmed/32328490
http://dx.doi.org/10.3389/fcell.2020.00165