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Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle
With the ability to switch between proliferative and contractile phenotype, airway smooth muscle (ASM) cells can contribute to the progression of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), in which airway obstruction is associated with ASM hypertrophy and hyperc...
Autores principales: | Baarsma, Hoeke A., Han, Bing, Poppinga, Wilfred J., Driessen, Saskia, Elzinga, Carolina R. S., Halayko, Andrew J., Meurs, Herman, Maarsingh, Harm, Schmidt, Martina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160303/ https://www.ncbi.nlm.nih.gov/pubmed/32328490 http://dx.doi.org/10.3389/fcell.2020.00165 |
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