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Limited expression of TLR9 on T cells and its functional consequences in patients with nonalcoholic fatty liver disease

BACKGROUND/AIMS: Toll-like receptors (TLRs) modulate T cell responses in diverse diseases. Co-stimulation of T cell activation via TLR9 induces production of interferon gamma (IFN-γ), priming of which is critical for differentiation of pro-inflammatory macrophages. These macrophages have a crucial r...

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Detalles Bibliográficos
Autores principales: Alegre, Nadia Soledad, Garcia, Cecilia Claudia, Billordo, Luis Ariel, Ameigeiras, Beatriz, Poncino, Daniel, Benavides, Javier, Colombato, Luis, Cherñavsky, Alejandra Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160356/
https://www.ncbi.nlm.nih.gov/pubmed/31795627
http://dx.doi.org/10.3350/cmh.2019.0074