Reactive fibrosis precedes doxorubicin‐induced heart failure through sterile inflammation

AIMS: Doxorubicin (DOX)‐induced heart failure has a poor prognosis, and effective treatments have not been established. Because DOX shows cumulative cardiotoxicity, we hypothesized that minimal cardiac remodelling occurred at the initial stage in activating cardiac fibroblasts. Our aim was to invest...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryo, Umemura, Masanari, Narikawa, Masatoshi, Hikichi, Mayu, Osaw, Kohei, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Tamura, Kouichi, Ishikawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160475/
https://www.ncbi.nlm.nih.gov/pubmed/31984667
http://dx.doi.org/10.1002/ehf2.12616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160475/
https://www.ncbi.nlm.nih.gov/pubmed/31984667
http://dx.doi.org/10.1002/ehf2.12616

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