The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression

Haploinsufficiency of SETD5 is implicated in syndromic autism spectrum disorder (ASD), but the molecular mechanism underlying the pathological role of this protein has remained unclear. We have now shown that Setd5(+/–) mice manifest ASD-related behavioral phenotypes and that the expression of ribos...

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Detalles Bibliográficos
Autores principales: Nakagawa, Tadashi, Hattori, Satoko, Nobuta, Risa, Kimura, Ryuichi, Nakagawa, Makiko, Matsumoto, Masaki, Nagasawa, Yuko, Funayama, Ryo, Miyakawa, Tsuyoshi, Inada, Toshifumi, Osumi, Noriko, Nakayama, Keiichi I., Nakayama, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160574/
https://www.ncbi.nlm.nih.gov/pubmed/32299058
http://dx.doi.org/10.1016/j.isci.2020.101030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160574/
https://www.ncbi.nlm.nih.gov/pubmed/32299058
http://dx.doi.org/10.1016/j.isci.2020.101030

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