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Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation

PURPOSE: Bile acids play an important role in Clostridioides difficile life cycle. Deoxycholate (DCA), one of the most abundant secondary bile acids, is known to inhibit vegetative growth and toxin production. However, limited data are available on the role of DCA on C. difficile sporulation. Here,...

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Detalles Bibliográficos
Autores principales: Usui, Yukino, Ayibieke, Alafate, Kamiichi, Yuko, Okugawa, Shu, Moriya, Kyoji, Tohda, Shuji, Saito, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160582/
https://www.ncbi.nlm.nih.gov/pubmed/32322715
http://dx.doi.org/10.1016/j.heliyon.2020.e03717