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A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions

Lysine methylation facilitates protein-protein interactions through the activity of methyllysine (Kme) “reader” proteins. Functions of Kme readers have historically been studied in the context of histone interactions, where readers aid in chromatin-templated processes such as transcription, DNA repl...

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Detalles Bibliográficos
Autores principales: Kupai, Ariana, Vaughan, Robert M., Dickson, Bradley M., Rothbart, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160673/
https://www.ncbi.nlm.nih.gov/pubmed/32328492
http://dx.doi.org/10.3389/fcell.2020.00241