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PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

Arginine methylation is a post-translational modification that regulates many biological processes. However, the role of arginine methylation in immune cells is not well studied. Here we report an essential role of protein arginine methyltransferase 5 (PRMT5) in T cell homeostasis and activation-ind...

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Detalles Bibliográficos
Autores principales: Tanaka, Yukinori, Nagai, Yasuhiro, Okumura, Mariko, Greene, Mark I., Kambayashi, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160866/
https://www.ncbi.nlm.nih.gov/pubmed/32328070
http://dx.doi.org/10.3389/fimmu.2020.00621