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PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling
Arginine methylation is a post-translational modification that regulates many biological processes. However, the role of arginine methylation in immune cells is not well studied. Here we report an essential role of protein arginine methyltransferase 5 (PRMT5) in T cell homeostasis and activation-ind...
Autores principales: | Tanaka, Yukinori, Nagai, Yasuhiro, Okumura, Mariko, Greene, Mark I., Kambayashi, Taku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160866/ https://www.ncbi.nlm.nih.gov/pubmed/32328070 http://dx.doi.org/10.3389/fimmu.2020.00621 |
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