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Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs

BACKGROUND: Hypothyroidism is a common complex endocrinopathy that typically has an autoimmune etiology, and it affects both humans and dogs. Genetic and environmental factors are both known to play important roles in the disease development. In this study, we sought to identify the genetic risk fac...

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Detalles Bibliográficos
Autores principales: Bianchi, Matteo, Rafati, Nima, Karlsson, Åsa, Murén, Eva, Rubin, Carl-Johan, Sundberg, Katarina, Andersson, Göran, Kämpe, Olle, Hedhammar, Åke, Lindblad-Toh, Kerstin, Rosengren Pielberg, Gerli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160888/
https://www.ncbi.nlm.nih.gov/pubmed/32299354
http://dx.doi.org/10.1186/s12864-020-6700-3