Cargando…
Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs
BACKGROUND: Hypothyroidism is a common complex endocrinopathy that typically has an autoimmune etiology, and it affects both humans and dogs. Genetic and environmental factors are both known to play important roles in the disease development. In this study, we sought to identify the genetic risk fac...
Autores principales: | Bianchi, Matteo, Rafati, Nima, Karlsson, Åsa, Murén, Eva, Rubin, Carl-Johan, Sundberg, Katarina, Andersson, Göran, Kämpe, Olle, Hedhammar, Åke, Lindblad-Toh, Kerstin, Rosengren Pielberg, Gerli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160888/ https://www.ncbi.nlm.nih.gov/pubmed/32299354 http://dx.doi.org/10.1186/s12864-020-6700-3 |
Ejemplares similares
-
A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12
por: Bianchi, Matteo, et al.
Publicado: (2015) -
Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs
por: Tengvall, Katarina, et al.
Publicado: (2016) -
A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs
por: Baranowska Körberg, Izabella, et al.
Publicado: (2014) -
Lack of Evidence for a Role of Islet Autoimmunity in the Aetiology of Canine Diabetes Mellitus
por: Ahlgren, Kerstin M., et al.
Publicado: (2014) -
Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds
por: Webster, Matthew T., et al.
Publicado: (2015)