Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes

BACKGROUND: Detection of DNA copy number alterations (CNAs) is critical to understand genetic diversity, genome evolution and pathological conditions such as cancer. Cancer genomes are plagued with widespread multi-level structural aberrations of chromosomes that pose challenges to discover CNAs of...

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Detalles Bibliográficos
Autores principales: Khalil, Ahmed Ibrahim Samir, Khyriem, Costerwell, Chattopadhyay, Anupam, Sanyal, Amartya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160937/
https://www.ncbi.nlm.nih.gov/pubmed/32299346
http://dx.doi.org/10.1186/s12859-020-3480-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160937/
https://www.ncbi.nlm.nih.gov/pubmed/32299346
http://dx.doi.org/10.1186/s12859-020-3480-3

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