PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease

BACKGROUND: Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryological gastrulation organizer that orchestrates vertebrate tissu...

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Detalles Bibliográficos
Autores principales: Thejer, Bashar M., Adhikary, Partho P., Teakel, Sarah L., Fang, Johnny, Weston, Paul A., Gurusinghe, Saliya, Anwer, Ayad G., Gosnell, Martin, Jazayeri, Jalal A., Ludescher, Marina, Gray, Lesley-Ann, Pawlak, Michael, Wallace, Robyn H., Pant, Sameer D., Wong, Marie, Fischer, Tamas, New, Elizabeth J., Fehm, Tanja N., Neubauer, Hans, Goldys, Ewa M., Quinn, Jane C., Weston, Leslie A., Cahill, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160964/
https://www.ncbi.nlm.nih.gov/pubmed/32293262
http://dx.doi.org/10.1186/s12860-020-00268-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160964/
https://www.ncbi.nlm.nih.gov/pubmed/32293262
http://dx.doi.org/10.1186/s12860-020-00268-z

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