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Study protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT: a multicentre, randomised controlled 2 × 2 factorial trial to investigate techniques to increase lumbar puncture success

BACKGROUND: The neonatal period carries the highest risk of bacterial meningitis (~ 1 in 5000 births), bearing high mortality (~ 10%) and morbidity (20–50%) rates. Lumbar puncture (LP) remains essential to the diagnosis of meningitis. Though LP is a common procedure in neonates, success rates are lo...

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Detalles Bibliográficos
Autores principales: Marshall, Andrew S. J., Sadarangani, Manish, Scrivens, Alexandra, Williams, Rachel, Yong, Jean, Bowler, Ursula, Linsell, Louise, Chiocchia, Virginia, Bell, Jennifer L., Stokes, Caz, Santhanadass, Patricia, Adams, Eleri, Juszczak, Edmund, Roehr, Charles C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160994/
https://www.ncbi.nlm.nih.gov/pubmed/32295554
http://dx.doi.org/10.1186/s12887-020-02050-8