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Study protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT: a multicentre, randomised controlled 2 × 2 factorial trial to investigate techniques to increase lumbar puncture success
BACKGROUND: The neonatal period carries the highest risk of bacterial meningitis (~ 1 in 5000 births), bearing high mortality (~ 10%) and morbidity (20–50%) rates. Lumbar puncture (LP) remains essential to the diagnosis of meningitis. Though LP is a common procedure in neonates, success rates are lo...
Autores principales: | Marshall, Andrew S. J., Sadarangani, Manish, Scrivens, Alexandra, Williams, Rachel, Yong, Jean, Bowler, Ursula, Linsell, Louise, Chiocchia, Virginia, Bell, Jennifer L., Stokes, Caz, Santhanadass, Patricia, Adams, Eleri, Juszczak, Edmund, Roehr, Charles C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160994/ https://www.ncbi.nlm.nih.gov/pubmed/32295554 http://dx.doi.org/10.1186/s12887-020-02050-8 |
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