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Solubility and Stability Advantages of a New Cocrystal of Berberine Chloride with Fumaric Acid

[Image: see text] BBC is a drug with a variety of activities but poor solubility. Cocrystal technology is an effective method to improve the solubility and stability of this type of compound. In this work, the cocrystal of BBC with fumaric acid was obtained at a stoichiometric ratio of 2:1. Studies...

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Detalles Bibliográficos
Autores principales: Yang, Dezhi, Cao, Junzi, Jiao, Lingtai, Yang, Shiying, Zhang, Li, Lu, Yang, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161028/
https://www.ncbi.nlm.nih.gov/pubmed/32309739
http://dx.doi.org/10.1021/acsomega.0c00692