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The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

BACKGROUND: Reversible cell cycle arrest (quiescence/G0) is characteristic of adult stem cells and is actively controlled at multiple levels. Quiescent cells also extend a primary cilium, which functions as a signaling hub. Primary cilia have been shown to be important in multiple developmental proc...

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Detalles Bibliográficos
Autores principales: Venugopal, Nisha, Ghosh, Ananga, Gala, Hardik, Aloysius, Ajoy, Vyas, Neha, Dhawan, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161131/
https://www.ncbi.nlm.nih.gov/pubmed/32293249
http://dx.doi.org/10.1186/s12860-020-00266-1