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The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts
BACKGROUND: Reversible cell cycle arrest (quiescence/G0) is characteristic of adult stem cells and is actively controlled at multiple levels. Quiescent cells also extend a primary cilium, which functions as a signaling hub. Primary cilia have been shown to be important in multiple developmental proc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161131/ https://www.ncbi.nlm.nih.gov/pubmed/32293249 http://dx.doi.org/10.1186/s12860-020-00266-1 |