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All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells

BACKGROUND: The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patients with non-small cell lung adenocarcinoma (NSCLC/ADC). CS...

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Detalles Bibliográficos
Autores principales: Yao, Wenxiu, Wang, Liyang, Huang, Huan, Li, Xin, Wang, Pinjia, Mi, Kun, Cheng, Jia, Liu, Huifen, Gu, Cuirong, Huang, Lingxiao, Huang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161137/
https://www.ncbi.nlm.nih.gov/pubmed/32293355
http://dx.doi.org/10.1186/s12885-020-06818-0