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Attenuation of intermittent hypoxia-induced apoptosis and fibrosis in pulmonary tissues via suppression of ER stress activation

BACKGROUND: Obstructive sleep apnea (OSA) is associated with pulmonary fibrosis and endothelial apoptosis in pulmonary tissues. Chronic intermittent hypoxia (IH) is considered to be the primary player in OSA, but the mechanisms underlying its effect on pulmonary tissues are unknown. Endoplasmic reti...

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Detalles Bibliográficos
Autores principales: Shi, Zhihui, Xu, Linhao, Xie, Hui, Ouyang, Ruoyun, Ke, Ya, Zhou, Rui, Yung, Wing-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161195/
https://www.ncbi.nlm.nih.gov/pubmed/32299413
http://dx.doi.org/10.1186/s12890-020-1123-0