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Introducing an α-Keto Ester Functional Group through Pt-Catalyzed Direct C–H Acylation with Ethyl Chlorooxoacetate

[Image: see text] Platinum-catalyzed selective C–H acylation of 2-aryloxypyridines with ethyl chlorooxoacetate provides an efficient way of introducing an α-keto ester functional group. The reaction is oxidant-free, additive-free, and, more significantly, free of any decarbonylative side reactions....

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Detalles Bibliográficos
Autores principales: Javed, Erman, Guthrie, Jacob D., Neu, Justin, Chirayath, George S., Huo, Shouquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161214/
https://www.ncbi.nlm.nih.gov/pubmed/32309750
http://dx.doi.org/10.1021/acsomega.0c00982