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Knockdown of lncRNA PVT1 alleviates high glucose-induced proliferation and fibrosis in human mesangial cells by miR-23b-3p/WT1 axis

BACKGROUND: Diabetic nephropathy (DN) is a severe complication of diabetes with type 1 and 2. Long non-coding RNAs (lncRNAs) are being found to be involved in the DN pathogenesis. In this study, we aimed to further explore the effect and underlying mechanism of plasmacytoma variant translocation 1 (...

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Detalles Bibliográficos
Autores principales: Zhong, Wen, Zeng, Jiaoe, Xue, Junli, Du, Aimin, Xu, Yancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161221/
https://www.ncbi.nlm.nih.gov/pubmed/32322310
http://dx.doi.org/10.1186/s13098-020-00539-x