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BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia

BACKGROUND: Forced polyploidization is an effective strategy for acute megakaryoblastic leukemia (AMKL) therapy and factors controlling polyploidization are potential targets for drug development. Although bone morphology protein 2-inducible kinase (BMP2K) has been implied to be a potential target f...

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Detalles Bibliográficos
Autores principales: Wang, Manman, Zhang, Tan, Zhang, Xuechun, Jiang, Zhou, Peng, Min, Huang, Zan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161226/
https://www.ncbi.nlm.nih.gov/pubmed/32322386
http://dx.doi.org/10.1186/s13578-020-00418-y