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BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia
BACKGROUND: Forced polyploidization is an effective strategy for acute megakaryoblastic leukemia (AMKL) therapy and factors controlling polyploidization are potential targets for drug development. Although bone morphology protein 2-inducible kinase (BMP2K) has been implied to be a potential target f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161226/ https://www.ncbi.nlm.nih.gov/pubmed/32322386 http://dx.doi.org/10.1186/s13578-020-00418-y |