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Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency

BACKGROUND: Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a promising intestinal stem cell and carcinoma stem cell marker. We examined the relationship between mismatch repair (MMR) protein deficiency and LGR5 expression in poorly differentiated (PD) colorectal carcinoma (CRC...

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Detalles Bibliográficos
Autores principales: Nakajima, Tomoyuki, Uehara, Takeshi, Iwaya, Mai, Kobayashi, Yukihiro, Maruyama, Yasuhiro, Ota, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161284/
https://www.ncbi.nlm.nih.gov/pubmed/32293346
http://dx.doi.org/10.1186/s12885-020-06791-8