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Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency
BACKGROUND: Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a promising intestinal stem cell and carcinoma stem cell marker. We examined the relationship between mismatch repair (MMR) protein deficiency and LGR5 expression in poorly differentiated (PD) colorectal carcinoma (CRC...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161284/ https://www.ncbi.nlm.nih.gov/pubmed/32293346 http://dx.doi.org/10.1186/s12885-020-06791-8 |