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Establishment of 5′–3′ interactions in mRNA independent of a continuous ribose-phosphate backbone

Functions of eukaryotic mRNAs are characterized by intramolecular interactions between their ends. We have addressed the question whether 5′ and 3′ ends meet by diffusion-controlled encounter “through solution” or by a mechanism involving the RNA backbone. For this purpose, we used a translation sys...

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Detalles Bibliográficos
Autores principales: Kluge, Florian, Götze, Michael, Wahle, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161349/
https://www.ncbi.nlm.nih.gov/pubmed/32111664
http://dx.doi.org/10.1261/rna.073759.119